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Benefits of Medical Marijuana

Cannabis-Derived Compound Has Potential to Treat Pancreatic Cancer

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Pancreatic Cancer Treat

A team of researchers from Harvard University discovered that a substance extracted from cannabis shows promise in treating cancer of the pancreas. Yahoo Lifestyle reports that scientists from the university’s Dana-Farber Cancer Institute developed the compound.

The role of Cannabis Flavonoids

The researchers studied how the medication, referred to as FBL-03G, affects pancreatic cancer cells. The experiment was done by exposing tumor cells from the pancreas of a patient. Animals with the same medical condition were also treated using FBL-03G.

The drug was derived from cannabis flavonoids. Flavonoids are substances found in plants that give them their well-defined and bright colors. Back in 1986, researchers also discovered that these compounds have anti-inflammatory effects.

In cannabis, flavonoids give the plants its distinctive aroma and flavor. These compounds also contribute to the anti-inflammatory and pain-relieving properties of marijuana.

According to the study published in Frontiers of Oncology, FBL-03G was able to destroy a significant amount of pancreatic tumor cells in mice.

A researcher who is working with the study, Wilfred Ngwa, said that the “tumor-targeted delivery of flavonoids” has shown positive results in killing the local and metastatic tumor cell. Ngwa remarked that this can “significantly [increase] survival” of pancreatic tumor patients.

Ngwa also remarked that the team’s research is the first to formulate a potentially new method of treating tumor of the pancreas.

The scientists also found out that the drug can also fight other types of cancer cells. The scientists were surprised to discover that FBL-03G can also target other cells. According to Ngwa, the treatment was able to block the development of new cells in other portions of the body.

Ngwa noted that the new treatment could also be affecting patients’ immune systems.

Challenges

While flavonoids are proven to have medicinal benefits, creating drugs derived from these compounds is proven to be challenging. Yahoo Lifestyle says that cannabis plants have a mere 0.14% of flavonoids. This means that in order to create substantial amounts of the drug, scientists would have to extract the compounds from a large number of plants.

However, researchers have discovered a way to produce flavonoids through genetic engineering. This is expected to allow investigators to explore the effects and potential impacts of these compounds.

Pancreatic cancer is one of the deadliest forms of cancer in the US. While it only makes up 3% of all cases in the country, it is foreseen as the second cause of death due to cancer by 2020.

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Benefits of Medical Marijuana

Can CBD Help with Tinnitus?

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High-pitched tones and ringing in your ears might already be a normal phenomenon to you, but this condition called tinnitus is actually a type of condition that many other people deal with, especially as they grow older over time.

People have heard that cannabidiol has been great for people dealing with different types of health conditions, from chronic pain, anxiety, insomnia and many others. With its prominence in the field, it comes as no surprise that there are many people who believe that this can help deal with tinnitus as well.

This article will let you in on what CBD products can do to help with tinnitus or if it can even help at all. Read on to find out.

What is Tinnitus?

Tinnitus is commonly described as a term when you hear ringing in your ears. Apart from ringing, you can also encounter high-pitched sounds, a buzzing or hissing sound, whistling, and other similar sounds. This particular condition can actually disrupt or interfere with how you normally hear or perceive sounds.

Tinnitus is often referred to as a symptom primarily because it points to other underlying conditions. For example, this can be caused by an ear injury, hearing loss due to age, high or low blood pressure, wax buildup in the ear canal, and problems relating to the neck, jaw, or teeth, to name a few.

Those who suffer from this condition for prolonged periods of time tend to develop stress, anxiety, and even depression.

This condition is treated and managed with the help of hearing aids, sound generators, environmental enrichment devices such as CD and mp3 recordings, and relaxation techniques.

How CBD Can Ease This Condition

Individuals have their own endocannabinoid system (ECS). This is comprised of the naturally-occurring cannabinoids in the body, enzymes, as well as cannabinoid receptors. The main goal of the ECS is to provide balance and regulation to our different bodily functions.

The cannabinoid receptors in our body, namely CB1 and CB2 receptors respond to cannabinoids we take, such as that of CBD.

Help Calm Nerves

CBD oil and other cannabidiol products have the capacity to help calm the nerves and the body. With cannabinoids being found to be of great help in neural processing within the auditory system, using CBD products can slow down these neural impulses. In turn, tinnitus, and the ringing it brings in your ears, can be toned down.

Potential to Reduce Hearing Loss

A study conducted in 2020 shows a positive disposition towards the use of cannabidiol and treating hearing conditions such as tinnitus. Since CBD is known to have anti-inflammatory and soothing effects, this can reportedly aid with the condition and reduce the chances of hearing loss.

Address Side Effects That Come with Tinnitus

As mentioned, people dealing with tinnitus, especially those who have dealt with this condition for a long time now, tend to develop stress, depression, and anxiety. CBD products are effective in reducing these feelings by interacting with the serotonin receptors in the brain.

The Bottom Line

There is still quite a way to go in studying the effects of CBD on tinnitus. However, with the preliminary studies conducted, it shows that cannabidiol is promising with its ability to manage symptoms of this condition.

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Benefits of Medical Marijuana

Best CBD for Sleep [VIDEO]

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CBD for Sleep

In recent years, CBD has become a buzzwordd for its ability to reduce anxiety and treat poor slumber. However, when it comes to addressing sleep problems, not all CBD is created equal. If you’re dealing with insomnia or any kind of bedtime issues, then find out which type of CBD should you use.

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Benefits of Medical Marijuana

How to Take Epidiolex and What Are Its Side Effects

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Epidiolex

Epilepsy sufferers with Lennox-Gastaut syndrome and Dravet syndrome can now use Epidiolex oral solution, which was approved by the US Food and Drug Administration on June 25, 2018. To our knowledge, this is the first marijuana-derived medication to be authorized by the FDA. For the first time, an FDA-approved medicine has been approved for the treatment of Dravet syndrome patients.

But aside from being the first-ever accepted CBD drug, do we really know what Epidiolex is? In this article, we will give you more information about this drug, the benefits, and side effects. Read on for more details.

Epidiolex and Its Effectiveness

Epidiolex
© CNNWire

To treat seizures caused by Lennox-Gastaut, Dravet, or Tuberous Sclerosis Complex (TSC) in persons 1 year of age and older, Epidiolex is prescribed. For those using the medicine, Epidiolex was found to reduce the number of seizures they had during clinical trials. Cannabidiol is the active component in this medication. It’s only
available under the brand name. Isn’t presently accessible as a generic medication.

How to Use Epidiolex

As instructed by your doctor, take Epidiolex medicine twice a day by mouth. With or without meals, this drug should be taken in the same manner for each and every dose. Choosing one method and sticking to it is essential. How much medicine you take is determined by your health status and any other drugs you may be taking.

If you’re taking any kind of medication, whether prescription or non-prescription, inform your doctor and pharmacist about it. Your doctor may instruct you to begin taking this medicine at a lower dosage and gradually raise your dosage in order to minimize the chance of adverse effects.

Your doctor may also gradually lower your dosage if you are told to stop using this medicine. Observe your doctor’s advice to the letter.
Using a specific spoon or measuring equipment, carefully measure the dosage. Avoid using a household spoon since you may not receive the right dosage.

Side Effects

Sleepiness, exhaustion, difficulty falling asleep or staying asleep, a lack of energy and a decrease in appetite, weight loss, or diarrhea are all possibilities. It’s important to notify your doctor or pharmacist if any of these side effects continue or worsen.

Remember that your doctor ordered this medicine because he or she believes that the benefits outweigh the risks. The majority of people who use this medicine do not have any substantial adverse effects.

Signs of liver damage should be reported to your doctor as soon as possible. Anti-seizure medicines may cause depression, suicidal thoughts, or other mental/mood issues in a tiny percentage of people.

The risk of a severe allergic response to this medication is quite low. However, if you detect any signs of a severe allergic response, such as a rash, itching, swelling, severe dizziness, or difficulty breathing, you should seek immediate medical attention.

How Much Is Epidiolex?

The price of Epidiolex might vary, just like the price of any other drug. Epidiolex may only be available at a specialized pharmacy. Specialty drugs are permitted to be sold at this pharmacy. Patients may need assistance from a healthcare professional in order to properly and efficiently utilize these medications.

Your insurance provider may demand that you obtain prior authorization before covering Epidiolex. As a result, before your insurance company will pay a prescription medication, your doctor and insurance company must talk about it.

Whether or not a medicine is covered by insurance depends on the outcome of the prior authorization request. Your insurance provider can help you determine whether or not you need prior permission for Epidiolex.

Conclusion

Though Epidiolex is an FDA-approved drug, there are no guaranteed similar good effects on every person. So if you ever encountered side effects that are listed above or anything that makes you feel uncomfortable after taking Epidiolex, it is recommended to consult your doctor immediately.

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