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Benefits of Medical Marijuana

Types of Cannabis: Sativa, Indica, and Hybrid

Daniel King

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Medical Cannabis

Medical marijuana has been all over the news recently after 33 states in the US, and many other countries around the world legalized the plant. A growing number of scientific studies backing up the use of the plant as medicine has convinced the governments of these states and countries. These experiments proved the wide range of health benefits that can be derived from cannabis. Since the legalization of this plant, you can find many health products and supplements being derived from medical cannabis.

When you shop for medical marijuana, either online or not, you might notice that the products are usually classified into three groups: sativa, indica, and hybrid. Each of these variants has a unique set of effects on the user. This article aims to clarify the differences between these three types of medical cannabis. This will give you a better understanding of the different kinds of weed, their characteristics, and the distinct therapeutic benefits that you can get from them.

Unique Traits of Sativa and Indica Plants

The term Cannabis, more commonly known as marijuana, refers to a genus of flowering plants belonging to the Cannabaceae family. It is one of the oldest crops cultivated by humans. Historians have records showing the use of this plant as early as 4,000 BC. Ancient civilizations in China and India used this plant for medicinal purposes primarily to relieve pain and to help cure other diseases.

While the exact number of species of the Cannabis genus is still disputed, two species have become popular in the scientific community: sativa and indica. They each have distinct characteristics that make them easy to distinguish from each other.

  • Sativa

Sativa plants grow well in countries near the equator where the length of the day seldom changes during the year. This plant is cultivated in countries and regions like Thailand, southern Africa, and Mexico. This plant can grow up to 20 feet tall so is better suited to outdoor cultivation. This plant takes almost six months to fully mature and, on average, it has a flowering time of between 60 and 90 days. Its leaves are thin and narrow and light green in hue.

  • Indica

Indica plants, on the other hand, are best suited to the more severe climate typically found in the mountainous regions of the Indian subcontinent (hence the name indica), Central Asia and the Middle East. Compared to sativa, indica plants are shorter and bushier, specifically adapted to enable them to survive the harsher environment. They also have high resin production to protect the leaves and trunks from turbulent conditions. This plant also matures quickly but has a shorter average flowering time (45-60 days). Its shorter growth height and flowering time make it more suitable for indoor cultivation. Unlike sativa, it has thicker and wider leaves and is darker green in color.

  • Hybrid

Just like in dogs, cats, and other pets, cross-breeding is a common phenomenon in plant cultivation. After thousands of years of cultivating the plants, pure cannabis strains, either a true indica or a true sativa variety, are a rarity nowadays. Most cannabis strains these days will be a combination of the two species and be either sativa-dominant or indica-dominant, and with the advancement in agricultural science and technology, growers can cultivate hybrid strains that are customized for different uses.

  • Ruderalis and Industrial Hemp: The Other Cannabis

While most medical journals only talk about sativa and indica, there is another type of cannabis known as ruderalis. It has physical features similar to indica. Aside from having thick foliage, it is also grown in harsher climates, like that found in the northern regions of the world such as Russia. It is the shortest cannabis variant, with an average height of 20-25 inches, and since it is grown in very cold areas, it matures early and has a fast flowering cycle.

Ruderalis contains harmful substances that can severely affect the brain. Hence, it is only cultivated by breeders and cultivators for experimentation and genetics.

Industrial hemp is a variety of the cannabis sativa plant. This plant is grown exclusively for industrial use. It can be processed and refined into different commercial items, including paper, clothing, textiles, paint, insulation materials, biodegradable plastics, biofuel, food ingredient, and animal feed.

Healing Properties of Sativa and Indica

Each species can affect the mind and body of a person differently. So, knowing the difference between the two will be very useful if you’re a patient seeking treatment using medical marijuana. According to research, here are some of the diseases and health conditions the two species can cure.

  • Sativa for Day

Scientists discovered that sativa contains substances that can uplift the mood of a person. Moreover, this plant also has chemicals that can increase the mental capacity of a person. It has properties that can improve focus and creativity and can also make a person more alert.

Because of these qualities, medical sativa is prescribed to relieve depression and attention deficit disorder (ADD). It can also be used to fight fatigue and creative blocks. It also has pain relieving qualities and can even stimulate the production of serotonin, the neurotransmitter responsible for regulating mood, learning, sleep, and appetite. With these properties, sativa is often used during the day.

  • Indica for Night

Indica contains compounds that induce a sedative and relaxing effect on the body. It can also calm the whole body, which makes it a perfect companion for relaxation and during meditation. It has properties that relieve stress and anxiety. Indica has a drowsy effect that can induce sleep, making this plant ideal to be used at night.

Indica can relieve insomnia and anxiety attacks, and it can also provide relief for nausea and chronic pain. What’s more, it can stimulate the appetite.

  • Hybrid: Best of Both Worlds

With the help of modern science, researchers were able to produce hybrids that contain both the qualities of sativa and indica. Hybrids are classified into three types: sativa-dominant, balanced, and indica-dominant.

  • With the sativa-dominant type, users can experience an active brain while experiencing a relaxed body feeling; the sativa-dominant hybrid is often used for relaxing both mentally and physically.
  • The balanced type has an equal ratio of sativa and indica This is typically used to provide an overall beneficial effect for both the mind and the body.
  • The indica-dominant type can put your body in a sedated state, but it only has a mild effect in your mind. Indica-dominant keeps you mentally awake while you feel a calm and relaxed sensation all over your body.

When deciding which type of medical marijuana to use, you’ll first need to establish the purpose for buying the weed. Do you want your body and mind to be stimulated for the day? Then purchase the sativa. If you want an effective sleeping aid and effective pain reliever, indica would be best for you. However, if you want the best of both worlds, pick the hybrid type.

As each of these three types has a different effect on the body, be sure to select the right strain and use according to the recommended dosage. Like any medicine, an overdose can cause harmful side effects. Since all the strains can affect the mind, experts caution users to take the correct dose of marijuana to avoid complications.

CBD: The Medical Compound from Weed

The three-type classification simplifies what effects each type has on the body. However, the effects of cannabis can be more complex and confusing in real life. As mentioned above, most cannabis strains nowadays are a mixture of sativa and indica. Thus, users cannot be sure if they will get the stimulating property of sativa or the calming property of indica. To get only the healing properties of cannabis from both species, scientists extract a substance called cannabidiol (CBD), which is present in all types of cannabis, including ruderalis, and industrial hemp.

When medical marijuana experts and researchers talk about medical marijuana, they often refer to CBD. CBD is one of at least 113 cannabinoids or substances that can be extracted from cannabis. Experts believe that this liquid is responsible for all the healing properties of weed. Just recently, CBD was declared safe for medical use by the WHO. The global body also provided a list of diseases that CBD can cure. Here are some of them:

  • Treatment of pimples and other skin diseases
  • Relief for chronic pain because of CBD’s anti-inflammatory properties
  • Capacity to rewire, heal and protect the nerves
  • Relieves symptoms of neurological diseases like epilepsy, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease
  • Treatment for anxiety and depression
  • Can improve the functioning of the heart and the cardiovascular system
  • Treatment for substance abuse
  • Can ease cancer symptoms

As you can see, most of these diseases are the ones cured by either sativa or indica.

Medical marijuana is now a popular medicine in the US and other parts of the world. You can now order medicinal weed online or offline. But before self-medicating with cannabis, be sure to consult a physician first to avoid experiencing the dangerous side-effects of wrong use and overdosage.

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Benefits of Medical Marijuana

Cannabis-Derived Compound Has Potential to Treat Pancreatic Cancer

Daniel King

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Pancreatic Cancer Treat

A team of researchers from Harvard University discovered that a substance extracted from cannabis shows promise in treating cancer of the pancreas. Yahoo Lifestyle reports that scientists from the university’s Dana-Farber Cancer Institute developed the compound.

The role of Cannabis Flavonoids

The researchers studied how the medication, referred to as FBL-03G, affects pancreatic cancer cells. The experiment was done by exposing tumor cells from the pancreas of a patient. Animals with the same medical condition were also treated using FBL-03G.

The drug was derived from cannabis flavonoids. Flavonoids are substances found in plants that give them their well-defined and bright colors. Back in 1986, researchers also discovered that these compounds have anti-inflammatory effects.

In cannabis, flavonoids give the plants its distinctive aroma and flavor. These compounds also contribute to the anti-inflammatory and pain-relieving properties of marijuana.

According to the study published in Frontiers of Oncology, FBL-03G was able to destroy a significant amount of pancreatic tumor cells in mice.

A researcher who is working with the study, Wilfred Ngwa, said that the “tumor-targeted delivery of flavonoids” has shown positive results in killing the local and metastatic tumor cell. Ngwa remarked that this can “significantly [increase] survival” of pancreatic tumor patients.

Ngwa also remarked that the team’s research is the first to formulate a potentially new method of treating tumor of the pancreas.

The scientists also found out that the drug can also fight other types of cancer cells. The scientists were surprised to discover that FBL-03G can also target other cells. According to Ngwa, the treatment was able to block the development of new cells in other portions of the body.

Ngwa noted that the new treatment could also be affecting patients’ immune systems.

Challenges

While flavonoids are proven to have medicinal benefits, creating drugs derived from these compounds is proven to be challenging. Yahoo Lifestyle says that cannabis plants have a mere 0.14% of flavonoids. This means that in order to create substantial amounts of the drug, scientists would have to extract the compounds from a large number of plants.

However, researchers have discovered a way to produce flavonoids through genetic engineering. This is expected to allow investigators to explore the effects and potential impacts of these compounds.

Pancreatic cancer is one of the deadliest forms of cancer in the US. While it only makes up 3% of all cases in the country, it is foreseen as the second cause of death due to cancer by 2020.

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Benefits of Medical Marijuana

DC Opens Marijuana Dispensaries to Out-of-State Patients

Daniel King

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DC Opens Marijuana Dispensaries

On Thursday, August 8, Mayor Muriel Bowser of Washington, DC announced that they will now accept medical marijuana cards from patients coming from any of the states in the U.S. with equivalent medical marijuana programs.

The new program will allow patients to purchase up to four ounces of medical marijuana each month. Patients from other states will only need to show their state-issued medical marijuana card to buy their medicines at any D.C. dispensary.

“This emergency rule making is patient-centric,” said Mayor Bowser in a statement. “It ensures medical marijuana patients from other states can obtain their needed medicine. It will also promote public safety by allowing visitors to obtain their medicine at one of the District’s six — soon to be seven — authorized marijuana dispensaries rather than forcing them to go without or patronizing the illegal market.”

The new policy will now expand the list of reciprocal acceptance from 19 to 27 states. The new additions include Alaska, Arizona, Arkansas, California, Nevada, New Mexico, New York, and Vermont. The District is also currently reviewing four other states to include in the list, namely Louisiana, Minnesota, Oklahoma, and West Virginia.

DC’s Medical Marijuana Reciprocity Amendment

First introduced in 2016, the Medical Marijuana Reciprocity Amendment includes a reciprocity arrangement that allows medical marijuana users to use their out-of-state registration cards to purchase medical cannabis in the District. The amendment took effect in April of 2018 and approved 19 states as part of its list of reciprocal acceptance. Under the said policy, patients enrolled in a medical marijuana program from other jurisdictions can access medical marijuana in the District of Columbia.

A year later, Mayor Bowser proposed the Safe Cannabis Sales Act of 2019, which allows the sale of recreational cannabis in Washington, D.C. with a 17 percent tax. It requires cannabis-focused businesses to meet a threshold of 60% ownership by D.C. residents, and 60% DC-native employees.

“We want to be able to regulate, we want to be able to make sure we are collecting our fair share in taxes, we want to invest those taxes in ways that affect communities that have been disproportionately affected, and we want to train and hire DC residents,” she said at the time. The bill is currently under DC Council review.

The latest emergency rule making is regarded by many to have opened an avenue for non-resident patients to access medication when visiting the nation’s capital.

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Benefits of Medical Marijuana

How Cannabis Affects the Human’s Brain

Stacey Wellington

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Cannabis and the Brain

Despite the political and social controversy surrounding cannabis, its medical benefits remain to be part of the public consciousness. From its pain-relieving features to its stress-reducing effect, this green plant has managed to leave a hopeful light in the medical community.

For years, many doctors and scientists have already attested to the incomparable promises the drug suggests, especially to the body’s command center. With this, various studies and researches are continuously being conducted to further expand on marijuana’s effect on the human brain.

Want to know what these several important discoveries are?

Here, we have compiled all the necessary findings modern science have discovered, and what further possibilities relating to cannabis and the brain may lie directly ahead.

Read on.

Cannabis and the Brain: How Does It Work?

Over the years, many substantial details about the relationship between cannabis and the brain have already been discovered. From identifying the active ingredient of the plant to determining how it specifically interacts with the brain, scientists have managed to arrive at different discoveries that have stunned the world.

After several decades of research, a new system called the endocannabinoid system has been unveiled to the public. From there, the question surrounding the enigmatic plant and the body’s command center has become an easier topic to grasp.

Human Brain and Cannabis

As explained by the National Institute on Drug Abuse, when a person smokes marijuana, the Tetrahydrocannabinol (THC), or the principal psychoactive constituent of cannabis, will pass through the lungs, go into the bloodstream, and reach the brain. Due to THC’s similar chemical structure with the brain chemical anandamide, the body recognizes the chemical and allows THC to attach and activate the chemical messengers of the endocannabinoid system called cannabinoid receptors.

Depending on the quantity consumed and the method of consumption, THC is likely to overwhelm the whole EC system. This, in turn, could interfere with the ability of the cannabinoid receptors to limit the amount of dopamine in the brain. This, in turn, throws the entire system off balance and stimulates the brain’s reward system, or a group of neural structures responsible for the body’s pleasure system. As a result, the brain generates higher dopamine levels, contributing to the feelings of euphoria or “high” associated with cannabis consumption.

From there, various mental and physical functions will be disrupted, and different effects are likely to occur in the body.

Here are a few you should know:

Health Benefits of Cannabis:

Over the decades, many medical breakthroughs have stemmed from a broad range of cannabis-related studies. Here, we present a few of the most promising medical solutions marijuana suggests to patients.

  • Mental health benefits

Although there is much more to learn about the effects of the plant to one’s mental health, various medical studies already prove marijuana’s potential in treating mental health disorders, especially depression, social anxiety, and PTSD.

In a study conducted by scientists at the University at Buffalo’s Research Institute on Addictions (RIA), the researchers have discovered how chronic stress may suppress the brain’s production of endocannabinoids or the natural chemical compounds responsible for maintaining homeostasis, which includes physical and emotional health. This, in turn, could lead to depression or post-traumatic stress disorder.

“Chronic stress is one of the major causes of depression,” explained RIA senior research scientist Samir Haj-Dahmane, Ph.D. “Using compounds derived from cannabis — marijuana — to restore normal endocannabinoid function could potentially help stabilize moods and ease depression.”

Moreover, in other preliminary studies, it was discovered that cannabis-based products help regulate emotional functions, such as mood and stress response. This stems from marijuana’s active ingredients, such as THC and CBD, which have been reported to reduce anxiety and tension by inducing relaxation.

However, the said discovery only remains true if cannabis is to be consumed in low dosage.

  • Enhance Cognitive Functions

As opposed to the common notion of how cannabis impairs cognitive functions, various studies revealed that the plant can actually pose a tremendous impact on one’s memory. In fact, in a study led by Harvard Medical School Affiliate McLean Hospital’s Staci Gruber, Ph.D., preliminary evidence suggests that marijuana consumption may not impair but may actually improve executive functioning in adults.

Due to the plant’s anti-inflammatory effects, many substantial pieces of evidence have been collected suggesting the drug’s ability to slow down the brain’s gradual degenerative process brought by aging.

In a review published in the Surgical Neurology International journal, researchers from the University of Pittsburg Medical Center discovered how recent neurological studies have used phytocannabinoids, or the naturally occurring cannabinoids found in the cannabis plant, in treating malignant brain tumors, Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, neuropathic pain, and childhood seizure disorders Lennox-Gastaut and Dravet syndromes.

‘CBD research in animal models and humans has shown numerous therapeutic properties for brain function and protection, both by its effect on the ECS directly and by influencing endogenous cannabinoids,” the researchers explained. “Broadly, CBD has demonstrated anxiolytic, antidepressant, neuroprotective anti-inflammatory, and immunomodulatory benefits. CBD decreases the production of inflammatory cytokines, influences microglial cells to return to a ramified state, preserves cerebral circulation during ischemic events, and reduces vascular changes and neuroinflammation.”

To date, researches concerning cannabis and other neurological disorders continue to dominate the medical realm. In fact, in a recent study, researchers have discovered how cannabis present antipsychotic effects on the brain, which suggest possible treatment for schizophrenia and dementia.

  • Could spur creativity

As opposed to the common stereotypes associated with marijuana users, various studies reveal that the use of cannabis could lead to increased mental creativity.

In fact, in a study conducted in 2012, researchers have suggested that cannabis’ ability to generate psychotomimetic symptoms, which include delusions and/or delirium, could actually lead to an increased level of creativity. According to the researchers, when a person experiences an altered state of mind, he or she is likely to see the world in a different perspective, engage in divergent thinking, and go beyond the limits of normal perception.

Some believe that this sudden spur of creativity could stem from the increased number of dopamine in the brain, which is associated with good cognitive flexibility.

  • Protect the brain after stroke

In a study conducted from the University of Nottingham, researchers have discovered how marijuana suggests possible neuroprotective treatment for stroke – at least for mice.

During the said research, the authors found how cannabinoids could help shrink the area of the brain affected by stroke, posing the drug’s potential to reduce brain damage.

“This meta-analysis of pre-clinical stroke studies provides valuable information on the existing, and importantly, missing data on the use of cannabinoids as a potential treatment for stroke patients,” explained lead author Dr Tim England. “The data are guiding the next steps in experimental stroke treatment in order to be able to progress onto initial safety assessments in a clinical trial.”

Given CBD’s and THC’s anti-inflammatory and anti-oxidant effects, the two compounds continue to attract attention from various medical groups and researchers. However, to date, recent medical studies identify CBD as a better long-term protective solution compared to THC.

  • Control Epileptic seizure

The use of cannabis for treating epilepsy has been studied and debated for years. However, despite the lack of sufficient data, many pieces of research have already established a few substantial pieces of evidence that put marijuana as a possible hope for patients suffering from epileptic seizures.

In fact, in a study conducted in 2003 published the Journal of Pharmacology and Experimental Therapeutics, it was found that marijuana extract and synthetic marijuana have stopped the seizures of epileptic rats for about 10 hours. This has revealed THC’s ability to control seizures by binding the brain cells responsible for controlling excitability and regulating relaxation.

In 2018, Epidolex, a drug derived from CBD, became the first FDA-approved cannabis-derived drug for treating two potentially fatal forms of severe childhood epilepsy, Lennox-Gastaut syndrome, and Dravet syndrome

  • Protect the brain from concussion and trauma

Just like in the case of stroke, some researchers believe that cannabis could help the brain repair itself after a traumatic injury due to its anti-inflammatory and antioxidant properties.

In fact, in a study published in the journal Cerebral Cortex, experiments have been done involving mice to prove marijuana’s ability to minimize the bruising of the brain and helped with healing mechanisms after a traumatic injury.

Earlier this year, Dr. Ethan Russo of the International Cannabis and Cannabinoids Institute presented his recent findings of the relationship of cannabis to head injuries. During his talk, he presented that CBD and THC may help prevent glutamate excitotoxicity or the pathological process by which nerve cells are damaged or killed.

He also presented THC and CBD as possible treatment solutions for chronic traumatic encephalopathy (CTE) symptoms experienced by football players and other athletes.

Conclusion:

For years, cannabis has stood as one of the stars in medical science. Although there is much more to discover about its effect on the body’s central command, these recent discoveries have opened up a space for patients and medical professionals to find the light amid the seemingly impossible quest for treatments.

Which among these medical findings surprised you the most?

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